1. to challenge to (a fight, game, etc.), to throw down the gauntlet, to contend for
2. to tackle (e.g. a problem), to attempt, to go after (a prize, record, etc.)
3. to pressure (someone) for sex, to make advances to
1. from (e.g. time, place, numerical quantity), since
2. from (originator), by
3. because, since
4. out of (constituent, part)
5. through (e.g. window, vestibule)
6. after, since
7. expresses sympathy or warning